Antiepileptic drugs prone to cause fetal deformity?

Many mothers know that during pregnancy can not be taking drugs, improper use may even induce fetal malformations, topiramate, also known as “topotecan”, is often used to treat adult epilepsy and migraine drugs. However, if taken in the first 3 months of pregnancy, most likely to lead to baby malformations! It is reported that a few days ago the French health magazine “TOPSANTE” related research for your mothers to provide cautious medication recommendations. The latest research by Brigham and Women’s Hospital in the United States shows that if topiramate is administered regularly during the first trimester of pregnancy, it may cause facial deformities in newborns – especially cleft lip and cleft palate, commonly known as “rabbit’s lips.” The report also said many medications were not recommended (and even banned) for pregnant women during the first trimester of pregnancy, including non-steroidal anti-inflammatory drugs (ibuprofen, aspirin and ketoprofen) Some cold medicines (especially vasoconstrictors), sedating antihistamines, antibiotics (cyclin, aminoglycosides, quinolones), and some medicines for the treatment of acne or psoriasis.

Pregnant women will encounter many minor illnesses, such as headache and cold, abdominal pain and diarrhea, or some chronic diseases such as high blood pressure. At this time, how should they use it? How to use scientific medication to the greatest extent possible to avoid harm to the fetus?

Try to avoid using any drugs during the first trimester of pregnancy

In the previous interview, the First Affiliated Hospital of Guangdong University of Obstetrics and Gynecology, Professor He Li said that the first three months of pregnancy try to avoid the use of any drug in the first trimester of pregnancy, the fetus at the crucial stage of organ differentiation and development, Drugs can be relatively sensitive. Therefore, it is recommended that pregnant women in the first three months should try to avoid medication, in three months later, the formation of fetal organs, stable development, the relative safety of medication, even if the external drug as well. At the same time pay attention to the dosage and time control, different from oral and injection timing quantitative use, the amount of external use in the smear, time and other aspects are not easy to control, therefore, should also be valued. For example, during pregnancy, especially in the first trimester of pregnancy, the need to use hormones smear ointment and other symptoms of dermatitis, be sure to go to the hospital for treatment, through the doctor after diagnosis and reuse, and must pay attention to the amount and time prescribed by the doctor to avoid prolonged, High-frequency, high-dose use.

For long-term medication for pregnant women with chronic diseases, or patients who have to take medicine during pregnancy, the pros and cons of the medication should be weighed in combination with the condition before using the drug. If the risk of using an excipient is less than the benefit, the medication may be used appropriately under the guidance of a physician. Therefore, during pregnancy, pregnant women must communicate well with their doctors, and doctors should have a comprehensive understanding of the history of pregnant women, medication history, etc., as well as the risks of prescription drugs to pregnant women and fetuses, as well as the latest information on drugs, understanding of drugs Side reactions, pregnant women should be fully informed, weighing the pros and cons, safe medication, in order to ensure the safety of mother and child.

Do not worry too much by your doctor’s orders

Dr. Sun Yat-sen Memorial Hospital of Sun Yat-sen Chen Chuxiong, deputy director of pharmacists have reminded us that early pregnancy is embryonic, fetal differentiation stage of development, susceptible to external factors and maternal disease, leading to fetal malformations or spontaneous abortion, should pay attention to disease prevention and anti-malware. Pregnancy sick find a doctor in time, according to the doctor’s advice on time do not have to worry too much about.