q: drink really cause cancer?
a: the study found that alcohol and its metabolic product acetaldehyde can induce cell gene mutation, but alcohol exposure to what extent, how to drink, can cause cell mutations, it is not clear. DetailPic
data diagram (for figure/visual China)
although long-term large amounts of alcohol liver, gastrointestinal tract, central nervous system damage is known, but in wine culture and has a long history of China, there is still a considerable number of wine lovers frequently & other; Cheers & throughout; .
however, at the beginning of the New Year 2018, a study published in the international top journal nature refresh on the Internet, the latest academic papers about drinking, carcinogenic concerns and controversy, caused widespread debate and detonating network.
epidemiology data shows that alcohol (ethanol), indeed, have a certain relationship with the incidence of some cancers, such as oral cancer, esophageal cancer, liver cancer, colorectal cancer, but the exact mechanism is unclear. Known, ethanol in the body of metabolic product & ndash; & ndash; Acetaldehyde is clear carcinogens. As a result, a large number of long-term drinking, acetaldehyde excessive accumulation in the body, can increase the risk of cancer.
published in the latest academic papers in nature is a study from Cambridge university, through animal experiments, the study found that alcohol and its metabolic product acetaldehyde can destroy the hematopoietic stem cell DNA structure directly, induce cell gene mutation, so as to increase the risk of cancer. It should be said that this is a very good study, to help us better cognitive mechanism of alcohol and cancer, explain the link between alcohol and cancer, has the vital significance.
we know that no matter in a white wine, beer or wine to drink, mainly by the liver into the body of ethanol metabolism, alcohol dehydrogenase ethanol metabolism of acetaldehyde, whereas acetaldehyde by acetaldehyde dehydrogenase metabolism for acetic acid and water, and further eliminate in vitro. Acetaldehyde can lead to drinkers appear red face, such as dizziness, nausea, and heart rate response.
found in this study, aldehyde dehydrogenase (ALDH2) mice, gene defects after the intake of alcohol to cell gene mutation. The results, to the Chinese people more alarming. Due to the crowd in China about 50% of defects or acetaldehyde dehydrogenase activity is insufficient, therefore, for this part of the crowd, once after drinking, acetaldehyde will not be able to timely for acetic acid metabolism, lead to acetaldehyde easier to accumulate in the body, increase the risk of cancer.
based on the study, even if a gene mutation in hematopoietic stem cells after heavy drinking, also does not mean that the cancer would happen for certain, can only say that may increase the risk of cancer. Due to the occurrence of cancer is a genetic, immune, and many other process and result of all kinds of factors, therefore, simply the gene mutation and cancer cells directly draw the equal sign, read too much into the study, is inappropriate.
although the study found that alcohol and its metabolic product acetaldehyde can induce cell gene mutation, but alcohol exposure to what extent, how to drink, can cause cell mutations, it is not clear. In addition, moderate drinking can lead to genetic mutations? There is cause genetic mutations safe drinking? Long-term and short-term heavy drinking alcohol drinking pattern, to the influence of induced mutation? These problems, more research remains to be elucidated. In addition, the study is carried out on animals, whether can fully explain the alcohol does to the human body, also is not clear.
therefore, we should see the study objective. Don’t talk about both colour change, drinking and cancer, will form a simple connection; Don’t ignore the study of the potential significance and value. We advocate the good life habit, don’t drink as much as possible, avoid long-term heavy drinking, reduce alcohol exposure, suspected of the flushing acetaldehyde dehydrogenase defects or inadequate activity especially should pay attention to avoid alcohol exposure, to maximize the lower alcohol may lead to cancer risk.